Severe Hypokalemic Paralysis as a Manifestation of a Mitochondrial Disorder

Severe Hypokalemic Paralysis as a Manifestation of a Mitochondrial Disorder. Josef Finsterer and Stefan Lässer; Tohoku J. Exp. Med., 2013, 231, 9-12

Mitochondrial disorder (MtD) is usually a multisystem disease due to impaired mitochondrial energy production. Severe hypokalemia resulting in muscle weakness and rhabdomyolysis has not been reported as a phenotypic feature of Mitochondrial Disease. …Mitochondrial disorder (MtD) is most frequently due to impaired energy production by the respiratory chain or the oxidative phosphorylation. The biochemical defect may result from mutations in the mitochondrial DNA or the nuclear DNA. MtD may manifest as a syndromic or non-syndromic disorder, or as a mono-organ or multi-organ disease (Finsterer 2012). read article

Last updated Sunday, November 9th, 2014

Periodic Paralysis International

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